Results 101 to 110 of about 656,141 (223)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Enhanced spectral signatures with Ag nanoarrays in hyperspectral microscopy for CNN-based microplastics classfication

open access: yesFrontiers in Chemistry
Microplastics are a pervasive pollutant in aquatic ecosystems, raising critical environmental and public health concerns and driving the need for advanced detection technologies.
Xinwei Dong   +8 more
doaj   +1 more source

Near-Infrared Reflectivity of Superconducting FeSe Thin Films

open access: yesIEEE Photonics Journal, 2019
We present an investigation on the intrinsic optical properties of superconducting FeSe thin films deposited on CaF2 substrates. It is found that the samples respond strongly to the near-infrared (NIR) irradiation in different temperature regimes.
Yanmin Zhang   +12 more
doaj   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

What Is the Optimal Sampling Time of Environmental Parameters? Fourier Analysis and Energy Harvesting to Reduce Sensors Consumption in Smart Greenhouses

open access: yesAgriEngineering
Smart greenhouses offer crucial solutions for reducing our atmospheric impact and resource waste. However, two fundamental challenges persist in their implementation, massive energy consumption and a high level of human intervention, particularly for ...
Cristian Bua   +2 more
doaj   +1 more source

On the Spectrum of Self--Adjoint Lévy Generators [PDF]

open access: yesarXiv, 2019
We investigate the spectrum of the generator of a self-adjoint transition semigroup of a (symmetric) L\'{e}vy process taking values in $d$--dimensional space.
arxiv  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

A function with support of finite measure and "small" spectrum [PDF]

open access: yesarXiv, 2017
We construct a function on the real line supported on a set of finite measure whose spectrum has density zero.
arxiv  

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