Results 161 to 170 of about 26,008,733 (290)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Quantitative evaluation of a deep learning-based noise reduction algorithm in digital radiography using noise power spectrum analysis. [PDF]

J Appl Clin Med Phys
Maruyama S, Saitou H.
europepmc   +1 more source

Photoacoustic spectrum analysis for spherical target size and optical property determination: A feasibility study. [PDF]

Photoacoustics, 2023
Dantuma M, Gasteau DB, Manohar S.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Removal of cardiogenic oscillations during pressure support ventilation using sliding window singular spectrum analysis: proof-of-concept. [PDF]

Biomed Eng Online
Pagano PP, Ciaccio EJ.
europepmc   +1 more source

Characteristics of sarcopenia subjects in arterial pulse spectrum analysis. [PDF]

Front Public Health, 2022
Ou Young T, Wu LW, Hsiu H, Peng TC, Chen WL.   +4 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Genetic spectrum analysis of high-carrier-frequency monogenic disorders based on whole-exome sequencing in the Chinese general population. [PDF]

Hum Genomics
Hao N, Lü Y, Bian J, Yin K, Xiao R, Hu P, Peng Y, Huang M, Qiao F, Xiao R, Liu Y, You Y, Jiang Y.   +12 more
europepmc   +1 more source

Fast Image-Level MRI Harmonization via Spectrum Analysis. [PDF]

Mach Learn Med Imaging, 2022
Guan H, Liu S, Lin W, Yap PT, Liu M.
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source