Results 41 to 50 of about 25,026,571 (299)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Objective: To evaluate the influence of opacity and the layering technique on the fluorescence of different composite resins. Materials and Methods: Two opacities (enamel and dentin) and the layering technique (enamel + dentin) of the composite resins ...
Carla Portocarrero-Flores+2 more
doaj +1 more source
Familiarity Affects Entrainment of EEG in Music Listening
Music perception involves complex brain functions. The relationship between music and brain such as cortical entrainment to periodic tune, periodic beat, and music have been well investigated.
Yuiko Kumagai+3 more
doaj +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Drawing Tower In-Line Fabrication and the Spectrum Analysis of Sampled Fiber Grating
Sampled fiber grating is a special superstructure fiber Bragg grating with a wide range of applications in many fields. In this work, based on drawing tower in-line fabrication system, a new preparation method of the sampled fiber grating is proposed and
Yu Zheng+5 more
doaj +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Monitoring the Dynamic Response of a Buried Polyethylene Pipe to a Blast Wave: An Experimental Study
Although the use of polyethylene (PE) pipelines has become increasingly widespread in recent years, few studies have addressed their seismic design and ability to withstand blast waves.
Dongwang Zhong+3 more
doaj +1 more source
Gut microbiota in patients with Alzheimer’s disease spectrum: a systematic review and meta-analysis
Context: Gut dysbiosis has been proposed as one of pathologies in patients with Alzheimer’s disease (AD) spectrum. Despite such enthusiasm, the relevant results remain substantially controversial.
Chun-Che Hung+4 more
semanticscholar +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley +1 more source