Results 41 to 50 of about 25,026,571 (299)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Influence of different opacities and layering technique of nanotechnology composite resins regarding the wavelength and fluorescence intensity: in vitro study

open access: yesJournal of Oral Research
Objective: To evaluate the influence of opacity and the layering technique on the fluorescence of different composite resins. Materials and Methods: Two opacities (enamel and dentin) and the layering technique (enamel + dentin) of the composite resins ...
Carla Portocarrero-Flores   +2 more
doaj   +1 more source

Familiarity Affects Entrainment of EEG in Music Listening

open access: yesFrontiers in Human Neuroscience, 2017
Music perception involves complex brain functions. The relationship between music and brain such as cortical entrainment to periodic tune, periodic beat, and music have been well investigated.
Yuiko Kumagai   +3 more
doaj   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Drawing Tower In-Line Fabrication and the Spectrum Analysis of Sampled Fiber Grating

open access: yesPhotonic Sensors, 2019
Sampled fiber grating is a special superstructure fiber Bragg grating with a wide range of applications in many fields. In this work, based on drawing tower in-line fabrication system, a new preparation method of the sampled fiber grating is proposed and
Yu Zheng   +5 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Monitoring the Dynamic Response of a Buried Polyethylene Pipe to a Blast Wave: An Experimental Study

open access: yesApplied Sciences, 2019
Although the use of polyethylene (PE) pipelines has become increasingly widespread in recent years, few studies have addressed their seismic design and ability to withstand blast waves.
Dongwang Zhong   +3 more
doaj   +1 more source

Gut microbiota in patients with Alzheimer’s disease spectrum: a systematic review and meta-analysis

open access: yesAging, 2022
Context: Gut dysbiosis has been proposed as one of pathologies in patients with Alzheimer’s disease (AD) spectrum. Despite such enthusiasm, the relevant results remain substantially controversial.
Chun-Che Hung   +4 more
semanticscholar   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

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