Results 71 to 80 of about 4,491,688 (341)

Monitoring and Analysis of the Operation Performance of Vertical Centrifugal Variable Frequency Pump in Water Supply System

open access: yesEnergies, 2023
The stable operation of a variable frequency pump is of great importance to the management of a water supply project. Analyzing the operation performance based on monitoring data is necessary for maintaining the stable operation of a variable frequency ...
Jianyong Hu   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Depression: Detecting the historical roots of research on depression prevention with reference publication year spectroscopy

open access: yesInternational Journal of Preventive Medicine, 2018
Background: Reference citation analysis and reference publication year can help to demonstrate the historical context of a research field. Therefore, this study aimed to determine the most important historical publications regarding depression prevention.
Ehsan Geraei   +2 more
doaj   +1 more source

PEMODELAN 3D STRUKTUR BAWAH PERMUKAAN GUNUNGAPI AGUNG PROVINSI BALI MENGGUNAKAN METODE GAYA BERAT

open access: yesJGE, 2020
Under surface structure, 3d modelling of Agung volcano in Bali had been conducted by using gravity methods. This research aims to identify the magma chamber and make a model below the surface of the Great Volcano of Bali Province by using gravity anomaly
Nasyratul Ilmi, Karyanto Karyanto
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Metal investigation of beams durable

open access: yesNauka ta progres transportu, 2011
Results of metal researches of long-term storage beams are considered. It is determined that the steel of beams meets the requirements of Norms. Their acceptability for construction of bridges is established.
Ya.A. Balabukh
doaj  

Ablação da fibrilação atrial por cateter com radiofreqüência guiada por mapeamento espectral endocárdico dos "ninhos de FA" em ritmo sinusal Radiofrequency catheter ablation of atrial fibrillation guided by spectral mapping of atrial fibrillation nests in sinus rhythm

open access: yesArquivos Brasileiros de Cardiologia, 2007
FUNDAMENTO: Através de mapeamento espectral-(ME) endocárdico em ritmo sinusal, observam-se dois tipos de miocárdio atrial: o compacto de espectro liso e o fibrilar de espectro segmentado ("Ninho de FA" [NFA]).
José Carlos Pachón Mateos   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy