Results 51 to 60 of about 2,120,679 (341)

A novel FAM83H variant causes familial amelogenesis imperfecta with incomplete penetrance

Molecular Genetics & Genomic Medicine, 2022
Background Amelogenesis imperfecta (AI) is known to be a monogenic genetic disease caused by a variety of genes demonstrating a wide spectrum of penetrance.
Rui‐Qi Bai, Wen‐Bin He, Qian Peng, Su‐Hui Shen, Qian‐Qian Yu, Juan Du, Yue‐Qiu Tan, Yue‐Hong Wang, Bin‐Jie Liu   +8 more
doaj   +1 more source

Effects of High Hydrostatic Pressure Pretreatment on the Functional and Structural Properties of Rice Bran Protein Hydrolysates

Foods, 2021
Rice bran protein (RBP) hydrolysis was conducted after high hydrostatic pressure (HHP) pretreatment. The structural and functional properties of HHP-pretreated rice bran protein hydrolysates (RBPH) were investigated.
Shirang Wang, Tengyu Wang, Yue Sun, Yingju Cui, Guoping Yu, Lianzhou Jiang   +5 more
doaj   +1 more source

Genomic and Functional Analysis of Emerging Virulent and Multidrug-Resistant Escherichia coli Lineage Sequence Type 648

Antimicrobial Agents and Chemotherapy, 2019
The pathogenic extended-spectrum-beta-lactamase (ESBL)-producing Escherichia coli lineage ST648 is increasingly reported from multiple origins. Our study of a large and global ST648 collection from various hosts (87 whole-genome sequences) combining core
K. Schaufler, T. Semmler, L. Wieler, D. Trott, J. Pitout, G. Peirano, J. Bonnedahl, M. Dolejská, I. Literák, Stephan Fuchs, N. Ahmed, M. Grobbel, C. Torres, A. McNally, D. Pickard, C. Ewers, N. Croucher, J. Corander, S. Guenther   +18 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The spectrum of functional neurological disorders: A retrospective analysis at a tertiary hospital in South Africa

South African Journal of Psychiatry, 2021
Background: Functional neurological disorders (FNDs) are commonly encountered in practice; however, there is a paucity of data in Africa. Aim: To identify and describe the clinical profile of patients presenting with FNDs, underlying medical and ...
Lavanya Naidoo, Ahmed I. Bhigjee
doaj   +1 more source

Abnormal Functional Connectivity of Resting State Network Detection Based on Linear ICA Analysis in Autism Spectrum Disorder

Frontiers in Physiology, 2018
Some functional magnetic resonance imaging (fMRI) researches in autism spectrum disorder (ASD) patients have shown that ASD patients have significant impairment in brain response.
Xia-an Bi, Junxia Zhao, Qian Xu, Qi Sun, Zhigang Wang   +4 more
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Disrupted Dynamic Functional Connectivity in Distinguishing Subjective Cognitive Decline and Amnestic Mild Cognitive Impairment Based on the Triple-Network Model

Frontiers in Aging Neuroscience, 2021
Background: Subjective cognitive decline and amnestic mild cognitive impairment (aMCI) were widely thought to be preclinical AD spectrum disorders, characterized by aberrant functional connectivity (FC) within the triple networks of the default mode ...
Chen Xue, Wenzhang Qi, Qianqian Yuan, Guanjie Hu, Honglin Ge, Jiang Rao, Chaoyong Xiao, Chaoyong Xiao, Jiu Chen, Jiu Chen   +9 more
doaj   +1 more source

Radiological and functional lung sequelae of COVID-19: a systematic review and meta-analysis

BMC Pulmonary Medicine, 2021
Background The coronavirus disease 2019 (COVID-19) causes a wide spectrum of lung manifestations ranging from mild asymptomatic disease to severe respiratory failure. We aimed to clarify the characteristics of radiological and functional lung sequelae of
M. So, H. Kabata, K. Fukunaga, H. Takagi, T. Kuno   +4 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source