Results 121 to 130 of about 2,512,854 (275)

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin   +11 more
wiley   +1 more source

Ports of Delaware Bay Industry and Public Sector Cooperation for Information Sharing / December 2010 [PDF]

open access: yes, 2010
(MIST Delaware Bay)The Maritime Information Sharing Taskforce (MIST) held its fourth event in Philadelphia on September 28-29, 2010. Using a participatory design approach, NPS researchers partnered with federal, state, local and commercial stakeholders ...
Englehorn, Lyla   +3 more
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Spectrum Sharing Methods in Coexisting Wireless Networks [PDF]

open access: yes, 2012
Radio spectrum, the fundamental basis for wireless communication, is a finite resource. The development of the expanding range of radio based devices and services in recent years makes the spectrum scarce and hence more costly under the paradigm of ...
Siddique, Mohammad Muttakin
core  

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Port of Honolulu Industry and Public Sector Cooperation for Information Sharing / Spring 2010 [PDF]

open access: yes, 2010
(MIST Honolulu)MIST held its third event in Honolulu on November 22-23, 2009. Using a participatory design approach, NPS researchers partnered with federal and commercial stakeholders to hold a workshop to assess the information sharing needs of security
Englehorn, Lyla|Hocevar, Susan   +2 more
core  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Industry and Public Sector Cooperation for Information Sharing: Ports of Long Beach & Los Angeles / September 2008 [PDF]

open access: yes, 2008
(MIST Long Beach/LA)On August 20-21, the Maritime Information Sharing Taskforce (MIST) held a workshop at the Los Angeles/Long Beach Port (LA/LB). This workshop was funded by the Assistant Secretary of Defense, (Department of Homeland Defense) and ...
Walsh, Wendy   +2 more
core  

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