Results 81 to 90 of about 904,551 (275)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Phase only transmit beamforming for spectrum sharing microwave systems [PDF]

open access: yes, 2017
This paper deals with the problem of phase-only transmit beamforming in spectrum sharing microwave systems. In contrast to sub-6 GHz schemes, general microwave systems require a large number of antennas due to its huge path loss.
Blanco, Luis   +3 more
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Cooperative Spectrum Sensing and Sharing in PD-NOMA Cognitive Radio Networks

open access: yesIEEE Access
Spectrum efficiency, spectrum sensing (SS) and sharing are core requirements of a reliable communication network to maximize the utilization of the scarce radio frequency spectrum.
Gilbert W. Machani, Tom Walingo
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Repeated Game-Inspired Spectrum Sharing for Clustering Cognitive Ad Hoc Networks

open access: yesInternational Journal of Distributed Sensor Networks, 2013
The paper studies the cooperative spectrum sharing among multiple secondary users (SUs) in a clustering cognitive ad hoc network. The problem is formulated as a repeated game with the aim of maximizing the total transmission rate of SUs.
Cuiran Li, Jianli Xie
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

A Reciprocal-Selection-Based ‘Win–Win’ Overlay Spectrum-Sharing Scheme for Device-to-Device-Enabled Cellular Network

open access: yesAlgorithms, 2018
This paper proposes a reciprocal-selection-based ‘Win⁻Win’ overlay spectrum-sharing scheme for device-to-Device-enabled cellular networks to address the resource sharing between Device-to-Device devices and the cellular users by using ...
Peng Li, Chenchen Shu, Jiao Feng
doaj   +1 more source

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