Results 191 to 200 of about 309,299 (297)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Online Personalized Normative Feedback to Foster Intention to Change and Help Seeking in Young Adults With Disordered Gambling and Trading Behaviors: Protocol for a Randomized Controlled Trial.

JMIR Res Protoc
Coloma-Carmona A, Carballo JL, Miró-Llinares F, Pérez-Jover V.   +3 more
europepmc   +1 more source

Pathways to family-centered healthcare: co-designing AI solutions with families in pediatric rehabilitation. [PDF]

Front Robot AI
Filogna S, Arras G, Turchi T, Prencipe G, Beani E, Bombonato C, Fedeli F, D'Alessandro G, Scrocco A, Sgandurra G.   +9 more
europepmc   +1 more source

The Poetics of Design Fiction [PDF]

, 2013
Knutz, Eva, Markussen, Thomas
core  

Speculating Backwards : How is Speculative Design Transferred into East Asia?

Speculating Backwards : How is Speculative Design Transferred into East Asia?
Session I : Design History and Design Education Speculative design has been well-known since the publication of the book Speculative Everything (MIT) in 2013, advocating design as a medium for promoting people's social dreams. This paper intends to take ‘speculative design’ as the research object with China as an example to explore the possibility of ...
openaire  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

A Case of Multiple Dural Arteriovenous Fistula-Like Findings Following Aneurysmal Subarachnoid Hemorrhage. [PDF]

Cureus
Pak S, Akimoto T, Shimohigoshi W, Umesaki A, Masuo O, Yamamoto T.   +5 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Reimagining the 'Lost' narratives of advanced dementia through literature and critical fabulation. [PDF]

Med Humanit
Schou-Juul F, Stončikaitė I, Fürholzer K, Irving K.   +3 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source