Results 31 to 40 of about 73,514 (252)
Design Research and Object-Oriented Ontology
In this paper we recount several research projects conducted at ImaginationLancaster (http://imagination.lancs.ac.uk) a Design-led research laboratory, all of which consider Object-Oriented Ontology (OOO).
Lindley Joseph +2 more
doaj +1 more source
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source
Speculative Requirements: Design Fiction and RE [PDF]
Many innovative software products are conceived, developed and deployed without any conventional attempt to elicit stakeholder requirements. Rather, they are the result of the vision and intuition of a small number of creative individuals who perceive a market opportunity that has been facilitated by the emergence of a new technology.
Andy Darby +2 more
openaire +2 more sources
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
Speculative Design in Education: Mapping the Landscape
This paper presents findings from a recent European-wide study on the use of Speculative Design approaches within education. The study included a survey of design educators and interviews with Speculative Design practitioners. This data has contributed to a mapping of the current educational landscape in Europe and will inform the development of an ...
Helgason, Ingi +5 more
openaire +2 more sources
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben +4 more
wiley +1 more source
Black Women’s Health Futures: Speculative Method as Structural Intervention
Public health research predominantly works in the present tense. It documents the disparities that structural racism and gendered racism produce and projects them forward, modeling futures as extrapolations of present harm. For Black women, positioned at
Whitney C. Irie +2 more
doaj +1 more source
The evolving field of reproductive technologies greatly alters our practices of conception and pregnancy. It is thus crucial to develop such innovations in a democratic and sustainable manner through public participation.
W. Willems +4 more
doaj +1 more source
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source

