Results 61 to 70 of about 31,090 (297)

Meillassoux and Heidegger – How to Deal with Things-in-Themselves?

open access: yesOpen Philosophy
In his critique of post-Kantian philosophy, Meillassoux expresses considerable doubts as to how it is capable of describing a world independent of man. He places Heidegger among the ranks of thinkers who are caught in the same trap of the thought-world ...
Leidlmair Karl
doaj   +1 more source

Dispositif, Matter, Affect, and the Real: Four Fundamental Concepts of Lyotard's Film-Philosophy

open access: yesFilm-Philosophy, 2019
Jean-François Lyotard's work remains a largely untapped resource for film-philosophy. This article surveys four fundamental concepts which indicate the fecundity of this work for current studies and debates.
Ashley Woodward
doaj   +1 more source

A short guide to material speculation

open access: yesInteractions, 2016
Speculative and fictional approaches have long been implemented in human-computer interaction and design techniques through scenarios, prototypes, forecasting, and envisionments. Recently, speculative and critical design approaches have reflectively explored and questioned possible, and preferable futures in HCI research.
Wakkary, Ron   +4 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Question that Says What it Does: On the Aperture of Materialism with Brassier and Bataille

open access: yesOpen Philosophy
Recent streams of thought arising in the wake of Speculative Realism have premised the possibility of materialism on the autonomy of the idea and the resistance of matter to ideal capture, thus stressing the mutual irreducibility of matter and idea. This
Vivaldi Jordi
doaj   +1 more source

Benjamin's Voices: Irresolution and Textual Practice in ON THE CONCEPT OF HISTORY

open access: yesMetacritic Journal for Comparative Studies and Theory, 2017
Benjamin’s final treatise On the Concept of History has generated significant criticism with its profound yet enigmatic statements on his historical materialism.
Lawrence S. Wang
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Marx on Historical Materialism [PDF]

open access: yes, 2017
Marx’s theory of historical materialism seeks to explain human history and development on the basis of the material conditions underlying all human existence. For Marx, the most important of all human activities is the activity of production by means of
Baur, Michael
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Vitalistic Approaches to Life in Early Modern England [PDF]

open access: yes, 2015
Vitalism has been given different definitions and diverse figures have been labelled as vitalists throughout the history of ideas. Concentrating on the seventeenth century, we find that scholars identify as vitalists authors who endorse notions that are ...
Szanto, Veronika
core  

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