Results 121 to 130 of about 59,319 (299)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Contesti in volo

open access: yesArdeth, 2018
Traditional design tools and procedures are not always appropriate to tackle the continuous movement of buildings and contexts. Starting from such apt consideration by Latour and Yaneva, this essay reflects on the issues that the introduction of movement
Pepe Barbieri
doaj  

For a history of effects: Hume and German anti-rationalism [PDF]

open access: yes, 2011
L'articolo analizza la ricezione del pensiero di Hume da parte di quello che I. Berlin ha definito l'anti-razionalismo tedesco, in pensatori come Hamann e, in particolare, H.F. Jacobi.
Sansonetti, Giuliano
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Buildings are not Processes: A Disagreement with Latour and Yaneva

open access: yesArdeth, 2017
The classic and traditional source on actor-network theory and architecture is a co-authored and well-know 2008 piece by Bruno Latour  and Albena Yaneva («Give Me a Gun and I Will Make All Buildings Move»: An Ant’s View of Architecture).
Graham Harman
doaj  

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

A Feeling for History? Bakhtin and `The Problem of Great Time' [PDF]

open access: yes, 2006
‘Great time’ has usually been seen as a ‘late term’ of Bakhtin’s. However, although it occurs most frequently in works written in the 1960s and 1970s, there is one known instance of its use in the 1940s.
SHEPHERD, D
core  

Speculative Realism and Other Heresies

open access: yes, 2014
This paper is a presentation of Speculative Realism that provides a brief summary of the most important protagonist’s positions: Quentin Meillassoux, Ray Brassier, Graham Harman and Iain Hamilton Grant. It includes a short history of this tendency starting from the Goldsmith workshop in April 2007 and mentioning more recent strategies and approaches ...
openaire   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

OBJECT-ORIENTED FEMINISM IN THE POSTHUMAN ENVIRONMENT

open access: yesВісник Харківського національного університету імені В.Н. Каразіна. Серія Філософія, філософські перипетії
The article’s narrative begins by considering the negative attitude of women philosophers, particularly feminist philosophers, towards speculative realism (hereinafter referred to as SR) and object-oriented ontology (hereinafter referred to as OOO). This
Nataliia Zahurska
doaj   +1 more source

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