Results 51 to 60 of about 16,838 (283)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Recent progress on phosphate-based electroactive materials for supercapacitor applications
Results in Surfaces and Interfaces, 2023 Currently, the global energy consumption is extensively increasing at a pace faster than the source advancement. The demand for renewable energy generation is an important scheme to settle energy crisis and climate changes which are prominent challenges ...
Abdudin G. Temam +6 more
doaj +1 more source
Implementation Planning: SPED Referral Flowchart
, 2021 No description available.
Haßler, Björn +3 more
openaire +1 more source
Fast Interpolation-based t-SNE for Improved Visualization of Single-Cell RNA-Seq Data [PDF]
Nature Methods, 2017 t-distributed stochastic neighbor embedding (t-SNE) is widely used for visualizing single-cell RNA-sequencing (scRNA-seq) data, but it scales poorly to large datasets.
G. Linderman +4 more
semanticscholar +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Design and implementation of a waterless solar panel cleaning system
Unconventional ResourcesManual cleaning of large solar installations is often labor-intensive and time-consuming, primarily due to the accumulation of dust on solar panels, which significantly impairs their efficiency.
Charity M. Nkinyam +5 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Advances in MoS2-Based ternary nanocomposites for high-performance electrochemical energy storage
Hybrid AdvancesThe field of rechargeable energy storage devices is actively exploring nanostructured materials with intricate morphologies due to several advantages. The integration of nanostructured materials into various electrodes, and rechargeable systems holds the
Seyoum A. Getaneh +5 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source