Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang +5 more
wiley +1 more source
Goal Setting in Speech-Language Pathology: A Pilot Test of a 'One-Size-Fits-All' Planning Framework. [PDF]
Hamilton JL, Hopkins EP, Kerr CM.
europepmc +1 more source
Exploring the online learning experience of first-year speech-language pathology students in a Johannesburg-based university. [PDF]
Barber N, Sher J.
europepmc +1 more source
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu +15 more
wiley +1 more source
Trends of female authorship in speech-language pathology publications over the last decade. [PDF]
Ganesan S +5 more
europepmc +1 more source
Precision Medicine as a New Frontier in Speech-Language Pathology: How Applying Insights From Behavior Genomics Can Improve Outcomes in Communication Disorders. [PDF]
Peter B +11 more
europepmc +1 more source
An electrochemical platform based on differential pulse amperometry enables real‐time, selective tracking of safinamide pharmacokinetics in the living brain with high spatiotemporal resolution. When integrated with electrophysiology, this approach reveals that drug‐induced suppression of vision‐related neuronal activity provides mechanistic insight ...
Xiaoke Nan +9 more
wiley +1 more source
ResearchGate as a strategic tool to enhance the scientific visibility in Speech-Language Pathology and Audiology. [PDF]
Fidêncio VLD.
europepmc +1 more source
MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang +15 more
wiley +1 more source
Outcomes Measures in Philippine Speech-Language Pathology Service Delivery. [PDF]
Marzan JC.
europepmc +1 more source

