Results 41 to 50 of about 171,164 (312)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Prevalence of swallowing difficulties in senior citizens: a combined cohort study in North Bengaluru

The Egyptian Journal of Otolaryngology
Background As India's aging population continues to grow, there remains a notable gap in empirical data on both self-reported and clinician-evaluated swallowing difficulties among older adults.
Renata Ammu Sajeev, Mereen Rose Babu, Srirangam Vijayakumar Narasimhan, Sandhya Koteshwara   +3 more
doaj   +1 more source

Jong kinders se gebruik van kommunikasiefunksies vóór en ná kogleêre inplanting

South African Journal of Communication Disorders, 2005
Hierdie artikel beskryf vyf jong kinders met kogleêre inplantings se gebruik van kommunikasiefunksies, in 'n poging om die invloed van die kinders se vroeë intensionele kommunikasiegedrag op hulle individuele kommunikasievaardighede ná kogleêre ...
Inge Kaltenbrünn, Brenda Louw, René Hugo   +2 more
doaj   +1 more source

Логопедія в культурно-історичному процесі 19-21 століть [PDF]

, 2018
У статті розглянуто історичний процес становлення і розвитку логопедії як науки і зокрема взаємовплив логопедії як науки і загального культурно-історичного процесу в Україні та світі.Представлено огляд результатів аналізу та узагальнення літературних ...
Тищенко, Владислав Володимирович, Царенко, Юлія Олександрівна   +1 more
core  

Knowledge persons accompanying patients in a Speech-Language Pathology school-clinic have about the work of speech-language pathologists [PDF]

, 2010
OBJETIVO: Avaliar o conhecimento dos acompanhantes de pacientes de uma clínica-escola de Fonoaudiologia sobre a atuação fonoaudiológica. MÉTODOS: Foram entrevistados 200 sujeitos, 100 do grupo experimental (GE) e 100 do grupo controle (GC). Foi realizada
DUARTE, Tâmyne Ferreira, LOPES-HERRERA, Simone Aparecida, PIMENTEL, Ana Gabriela Lopes   +2 more
core   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Speech and language therapy/pathology: Perspectives on a gendered profession [PDF]

, 2013
Background: The Speech and Language Therapy/Pathology (SLT/SLP) profession is characterised by extreme ‘occupational sex segregation’, a term used to refer to persistently male or female-dominated professions. Men make up only 2.5% of all SLTs in the UK,
American-Speech-Language-Hearing Association, Anker, Berndt, Blows, Boyd, Bradley, Byrne, Byrne, Byrne, Curtis, Duffin, Edley, England, Fairclough, Farmer, Francis, Glaser, Gottfredson, Greenwood, House of Commons (HOC) Trade and Industry Committee, Jacobs, Krueger, Krueger, Litosseliti, Litosseliti, Markham, Mcallister, Mckinson, Meadus, Miles, Mosheim, Muldoon, Office for National Statistics (ONS), Ortner, Patterson, Pringle, Sheridan, Speech Pathology Australia, Van Dijk, Werven, Whitehouse, Williams   +41 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Audiology practice management in South Africa: What audiologists know and what they should know

South African Journal of Communication Disorders, 2015
Background: In future, the South African Department of Health aims to purchase services from accredited private service providers. Successful private audiology practices can assist to address issues of access, equity and quality of health services. It is
Deidré Breytenbach, Alta Kritzinger, Maggi Soer   +2 more
doaj   +1 more source