Results 61 to 70 of about 1,469,086 (346)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Auditory and Preverbal Skill Improvements between Early and Late Cochlear Implantees: Evidence from LittlEARS Questionnaire [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Children with hearing loss are either fitted with hearing aid or implanted with Cochlear implants and Brainstem Implants. It is essential for these children to undergo intervention during the critical period, a lot of objective evidences ...
KR Rahul, Deepika Jayachandran, Ranjith Rajeswaran, Abishek Umashankar   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Speech-to-Speech Translation For A Real-world Unwritten Language [PDF]

, 2022
Peng‐Jen Chen, Kevin Tran, Yilin Yang, Jingfei Du, Justine Kao, Yu-An Chung, Paden Tomasello, Paul-Ambroise Duquenne, Holger Schwenk, Hongyu Gong, Hirofumi Inaguma, Sravya Popuri, Changhan Wang, Juan Pino, Wei-Ning Hsu, Ann Lee   +15 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Communication Abilities as A Correlate of Academic Achievement

Journal Riphah College of Rehabilitation Sciences, 2017
Background: Communication is the essential link between two persons. The communication competency of a person relates to the ability of the communicator who can render successful information processing at the other end, i.e. the listener.
Munawar Ahmad Malik, Hafsa Noreen, Arshad Mahmood, Attiya Ismail, Nayab Iftikhar, Maroof Khan   +5 more
doaj  

Executive functions in mid-life adults with mild sensorineural hearing loss compared with age-matched controls with normal hearing

The Egyptian Journal of Otolaryngology
Purpose This study explores the relationship between sensorineural hearing loss (SNHL) in mid-life adults and cognitive function, focusing on executive functions.
Pooja Chandrashekar, Hema Nagaraj
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Personal VAD 2.0: Optimizing Personal Voice Activity Detection for On-Device Speech Recognition [PDF]

, 2022
Shaojin Ding, Rajeev Rikhye, Qiao Liang, Yanzhang He, Quan Wang, Arun Narayanan, Tom O’Malley, Ian McGraw   +7 more
openalex   +1 more source