Results 71 to 80 of about 1,316,140 (262)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Speech Sound Disorders of Children With Mental Delays
Human Research in RehabilitationThis study aimed to investigate the speech sounds processes of children diagnosed with mental delays. Additionally, we explored all the sounds of the Albanian language, in level of articulation. We recruited 50 children, including 25 boys and 25 girls,
Muljaim Kacka +3 more
doaj +1 more source
The effect of visual speech timing and form cues on the processing of speech and nonspeech
, 2013 Auditory speech processing is facilitated when the talker's face and head movements (visual speech) can be seen. This effect occurs over a range of spoken word tasks, e.g., for spoken word identification (determining which word was presented) and for ...
Davis, Chris (R11605) +1 more
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
South African Journal of Communication Disorders, 2015 Background: Upon graduation, newly qualified speech-language therapists are expected to provide services independently. This study describes new graduates’ perceptions of their preparedness to provide services across the scope of the profession and ...
Shajila Singh +7 more
doaj +1 more source
Spontaneous and explicit speech imitation
, 2013 The single word speech shadowing task typically produces spontaneous imitation of the speech of the shadowed talker (the model). This task has been used as a tool for examining speech convergence in a non-social setting and has provided data for claims ...
Demirdjian, Ruben (R17699) +2 more
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Multilingual children with speech sound disorders : position paper [PDF]
, 2012 Individuals and societies benefit when children are supported to become competent communicators. Most children learn to speak one, two, or multiple languages competently.
International Expert Panel on Multilingual Children’s Speech +1 more
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