Results 91 to 100 of about 1,316,140 (262)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Multi-domain clinical profile of an individual with cutis laxa syndrome: A case report

open access: yesThe Egyptian Journal of Otolaryngology
The purpose of this paper is to highlight the speech-language and audio-vestibular evaluation of an individual with Cutis Laxa Syndrome (CLS). CLS is a rare genetic disorder that primarily affects the skin, leading to a loose, saggy, and prematurely aged
Murali Subhiksha   +3 more
doaj   +1 more source

Conversing in the presence of a competing conversation : effects on speech production

open access: yes, 2011
International audienceHow does a background conversation affect a foreground con-versation? In this scenario, and unlike traditional studies of noise-induced speech modification (Lombard speech), listeners have to cope with the additional challenge of ...
Aubanel, Vincent (R17640)   +3 more
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

La voix d’Hélène dans l’épopée homérique : fiction et tradition

open access: yesCahiers Mondes Anciens, 2012
Homeric scholarship usually considers Helen as an allegorical substitute for the poet or the Muses. But the homeric Helen is a fictional character, staged in the narrative by the poet who considers her as a central character for his epics.
Sylvie Perceau
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

"A Very Soft or Long Attack and Release" or Heyyyyy: Queer Extensities

open access: yesLateral, 2014
Amalle Dublon's piece takes up extensity — the drawing out of certain sounds in verbal speech — as a phonic gesture that exceeds the temporal (and we might argue productive) regulations of merely representative, coded speech.
Amalie Dublon
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Auditory-visual speech to infants and adults : signals and correlations

open access: yes, 2012
We investigated how the properties of Infant Directed Speech (IDS) and Adult Directed Speech (ADS) differed in acoustics and in speech-related articulation.
Davis, Chris (R11605)   +2 more
core  

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

open access: yesMolecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani   +7 more
wiley   +1 more source

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