Results 71 to 80 of about 3,161,098 (343)
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Effect of Hearing Impairment on Receptive Language Development among Children Between 2-5 Years
Journal Riphah College of Rehabilitation Sciences, 2017 Background: Hearing is the process of sound reception by the ear, its manipulation and conduction to brain. The ability to understand words and language is called receptive language.
Abdul Qadeer +4 more
doaj
Molecular Oncology, EarlyView.This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo +6 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Simulating dysarthric speech for training data augmentation in clinical speech applications
, 2018 Training machine learning algorithms for speech applications requires large, labeled training data sets. This is problematic for clinical applications where obtaining such data is prohibitively expensive because of privacy concerns or lack of access.
Berisha, Visar +3 more
core +1 more source
Imperial strategy of cancer cells through mitochondrial transfer
Molecular Oncology, EarlyView.Cangkrama et al. demonstrated that cancer cells donate their mitochondria to fibroblasts through mitochondrial transfer, reprogramming them into ‘MitoCAF’. Likewise, our group has identified mitochondrial transfer from cancer cells to tumor infiltrating lymphocytes, resulting in mitochondrial ‘hijack’ and impaired antitumor immunity.
Takamasa Ishino, Yosuke Togashi
wiley +1 more source
Mixture Density Networks, Human Articulatory Data and Acoustic-to-Articulatory Inversion of Continuous Speech [PDF]
, 2001 Researchers have been investigating methods for retrieving the articulation underlying an acoustic speech signal for more than three decades. A successful method would find many applications, for example: low bit-rate speech coding, helping individuals ...
Richmond, K.
core
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
Speech enhancement using deep learning [PDF]
, 2017 This thesis explores the possibility to achieve enhancement on noisy speech signals using Deep Neural Networks. Signal enhancement is a classic problem in speech processing.
Badescu, Dan Mihai
core
Constrained structure of ancient Chinese poetry facilitates speech content grouping
, 2020 Ancient Chinese poetry is constituted by structured language that deviates from ordinary language usage [1, 2]; its poetic genres impose unique combinatory constraints on linguistic elements [3].
Blohm, S. +5 more
core +1 more source