Results 41 to 50 of about 8,111,558 (275)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Analysis of speech prosody using WaveNet embeddings : The Lombard effect [PDF]

open access: yes, 2020
We present a novel methodology for speech prosody research based on the analysis of embeddings used to condition a convolutional WaveNet speech synthesis system.
Juraj Šimko   +5 more
core   +1 more source

Towards Application of Speech Act Theory to Opinion Mining

open access: yesCognitive Studies | Études cognitives, 2016
Towards the Application of Speech Act Theory to Opinion Mining The paper refers to the pragmatics’ perspective on opinion mining in Polish and English, inspired by the discrepancy between the coverage of sentiment analysis and the market demand.
Agnieszka Magdalena Pluwak
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Speech act of the characters in disney movie encanto

open access: yes, 2023
This study aims to analyze and explain how the speech act conveyed in Encanto movie directly or indirectly using John R. Searle theory. The writer uses qualitative analysis method in conducting this research.The researcher found thirty data of ...
Moh. supardi,, Yoga eka permana .
core  

CLASSIFICATION AND WAYS OFEXPRESSION OF SUGGESTIVES

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2013
The article focuses on different classifications of speech acts called suggestives in the framework of speech acts theory on the basis of modern English literature.
Alexandra Michailovna Kochergan
doaj  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Approval, Praise, Compliment and Flattery in Speech Act Theory

open access: yesЗаписки з романо-германської філології, 2016
The article outlines approval, praise, compliment and flattery in terms of Speech Act Theory. The illocutionary aims of approval, praise, compliment and flattery speech acts have been differentiated.The author offers her own definitions of approval ...
Н. О. Бігунова
doaj   +1 more source

Analyzing the speech actions of Imam Khomeini’s Will; based on Searle and Austin model [PDF]

open access: yesعلوم سیاسی, 2019
The aim of this study is the linguistic analysis of Imam Khomeini’s Will based on Searle and Austin theory of speech act and willing to answer to this question that According to Searle and Austin's speech act theory, what actions it will have, and what ...
ebrahim tobeyani   +2 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

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