Results 131 to 140 of about 392,381 (314)

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Voice as a sensitive biomarker for predicting exercise intensity: a modelling study

open access: yesFrontiers in Physiology
ObjectiveThis study investigates the potential of using voice as a sensitive omics marker to predict exercise intensity.MethodsNinety-two healthy university students aged 18–25 participated in this cross-sectional study, engaging in physical activities ...
Shuyi Zhou   +9 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Prosody for the eyes: quantifying visual prosody using guided principal component analysis

open access: yes, 2010
Although typically studied as an auditory phenomenon, prosody can also be conveyed by the visual speech signal, through increased movements of articulators during speech production, or through eyebrow and rigid head movements.
Jeesun Kim   +7 more
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Screening for early Alzheimer’s disease: enhancing diagnosis with linguistic features and biomarkers

open access: yesFrontiers in Aging Neuroscience
IntroductionResearch has shown that speech analysis demonstrates sensitivity in detecting early Alzheimer’s disease (AD), but the relation between linguistic features and cognitive tests or biomarkers remains unclear.
Chia-Ju Chou   +14 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Voice-Based Detection of Parkinson’s Disease Using Machine and Deep Learning Approaches: A Systematic Review

open access: yesBioengineering
Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor symptoms, among which vocal impairment is one of the earliest and most prevalent. In recent years, voice analysis supported by machine learning (ML)
Hadi Sedigh Malekroodi   +2 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Pitch-scaled estimation of simultaneous voiced and turbulence-noise components in speech

open access: yes, 2001
Almost all speech contains simultaneous contributions from more than one acoustic source within the speaker's vocal tract. In this paper, we propose a method -- the pitch-scaled harmonic filter (PSHF) -- which aims to separate the voiced and turbulence ...
Shadle, Christine H.   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy