Results 51 to 60 of about 251,655 (262)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Towards a vividness in synthesized speech for audiobooks

open access: yesEesti ja Soome-ugri Keeleteaduse Ajakiri, 2019
The goal of this study was to determine which acoustic parameters are significant in differentiating the speaking styles of a narrator and that of male and female characters as voiced by a reader of audiobooks.
Hille Pajupuu, Rene Altrov, Jaan Pajupuu
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Leveraging Deep Learning for Fine-Grained Categorization of Parkinson’s Disease Progression Levels through Analysis of Vocal Acoustic Patterns

open access: yesBioengineering
Speech impairments often emerge as one of the primary indicators of Parkinson’s disease (PD), albeit not readily apparent in its early stages. While previous studies focused predominantly on binary PD detection, this research explored the use of deep ...
Hadi Sedigh Malekroodi   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Speech Analysis

open access: yesSpeech Analysis
identifier:oai:t2r2.star.titech.ac.jp ...
openaire   +2 more sources

Real-time emotion identification system using voice information

open access: yesNihon Kikai Gakkai ronbunshu
Conventional speech emotion identification often uses sentence units as analysis length generally. However, human emotions frequently change their emotions instantaneously when they hear a specific word or keyword that affects each speaker’s emotion, and
Riki FUKUYOSHI, Masashi NAKAYAMA
doaj   +1 more source

Speech frame implementation for speech analysis and recognition

open access: yes, 2021
7 pages, 27 ...
Konev, A. A.   +2 more
openaire   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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