Results 61 to 70 of about 251,655 (262)

A Methodology for Recognition of Emotions Based on Speech Analysis, for Applications to Human-Robot Interaction. An Exploratory Study

open access: yesPaladyn, 2014
A system for recognition of emotions based on speech analysis can have interesting applications in human-robot interaction. In this paper, we carry out an exploratory study on the possibility to use a proposed methodology to recognize basic emotions ...
Rabiei Mohammad, Gasparetto Alessandro
doaj   +1 more source

SPEECH ACTS ANALYSIS OF DONALD TRUMP’S SPEECH

open access: yesPROJECT (Professional Journal of English Education), 2019
This research deals with the types of illocutionary acts in Donald Trump’s Inaugural Speech. The research concerns with illocutionary act produced by Donald Trumps as a President of American. The aim of this research was to analyze the types of illocutionary speech act which was dominantly used in that speech.
Nura Siti Mufiah   +1 more
openaire   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Study of effects of surgical treatment in the larynx area on the speech signal

open access: yesArchives of Acoustics, 2008
The speech signal emitted by humans may be a source of useful diagnostic and prognostic information. The signal may become, indirectly by some selected parameters, an additional source of information concerning the condition of the ...
Wiesław WSZOŁEK   +2 more
doaj  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Assessment of Speech Intelligibility in Parkinson’s Disease Using a Speech-To-Text System

open access: yesIEEE Access, 2017
Patients with Parkinson's disease (PD) may have difficulties in speaking because of reduced coordination of the muscles that control breathing, phonation, articulation, and prosody.
Giovanni Dimauro   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Speech Segregation based on Pitch Track Correction and Music-Speech Classification

open access: yesAdvances in Electrical and Computer Engineering, 2012
A novel approach for pitch track correction and music-speech classification is proposed in order to improve the performance of the speech segregation system.
KIM, H.-G.   +4 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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