Results 31 to 40 of about 168,660 (312)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Wideband acoustic immittance for assessing middle ear functioning for preterm neonates in the neonatal intensive care unit

South African Journal of Communication Disorders, 2017
Background: The primary aim of newborn hearing screening is to detect permanent hearing loss. Because otoacoustic emissions (OAEs) and automated auditory brainstem response (AABR) are sensitive to hearing loss, they are often used as screening tools.
Nandel Gouws, De Wet Swanepoel, Leigh Biagio de Jager   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Erratum: Wideband acoustic immittance for assessing middle ear functioning for preterm neonates in the neonatal intensive care unit

South African Journal of Communication Disorders, 2018
No abstract available.
Nandel Gouws, De Wet Swanepoel, Leigh Biagio de Jager   +2 more
doaj   +1 more source

Knowledge persons accompanying patients in a Speech-Language Pathology school-clinic have about the work of speech-language pathologists [PDF]

, 2010
OBJETIVO: Avaliar o conhecimento dos acompanhantes de pacientes de uma clínica-escola de Fonoaudiologia sobre a atuação fonoaudiológica. MÉTODOS: Foram entrevistados 200 sujeitos, 100 do grupo experimental (GE) e 100 do grupo controle (GC). Foi realizada
DUARTE, Tâmyne Ferreira, LOPES-HERRERA, Simone Aparecida, PIMENTEL, Ana Gabriela Lopes   +2 more
core   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Development of a clinical feeding assessment scale for very young infants in South Africa

South African Journal of Communication Disorders, 2016
Background: There is a need for validated neonatal feeding assessment instruments in South Africa. A locally developed instrument may contribute to standardised evaluation procedures of high-risk neonates and address needs in resource constrained ...
Mari Viviers, Alta Kritzinger, Bart Vinck   +2 more
doaj   +1 more source

What speech-language pathologists and students of speech-pathology understand as fluency and disfluency [PDF]

, 2007
PURPOSE: to check the understanding of current students (those who are in 3rd and 4th year) and Speech-Language Pathology professionals about the concepts of fluency and dysfluency, the components and aspects that affect fluency and the sorts of speech ...
Chiappetta, Ana Lúcia de Magalhães Leal, Merlo, Sandra, Oliveira, Ana Maria do Carmo Carvalho de, Ribeiro, Ignês Maia   +3 more
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Gestational age and birth weight variations in young children with language impairment at an early communication intervention clinic

South African Journal of Communication Disorders, 2018
Background: South Africa presents with high preterm birth (PTB) and low birth weight (LBW) rates (14.17%). Numerous conditions characterised by language impairment are associated with LBW and/or PTB.
Lauren C. Fouché, Alta Kritzinger, Talita le Roux   +2 more
doaj   +1 more source