Measuring and understanding patterns of change in intervention studies with children: implications for evidence-based practice [PDF]
Purpose: Comparisons across studies of the effects of intervention are problematic. Such analyses raise both methodological and statistical challenges.
Dockrell, Julie, Law, James
core +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Speech-Language Pathology and Occupational Therapy interface: an integration of scientific knowledge
Objective: to analyze the national scientific production of Speech-Language Therapy in the interface with Occupational Therapy (OT) based on an integrative literature review.
Elisandra Santos Mendes Garcia +2 more
doaj +2 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Predictors of Language and Speech Development in Boys with Duchenne Muscular Dystrophy
The aim of this review is to provide a brief summary of the current knowledge regarding the predictors of language and speech development in boys with Duchenne Muscular Dystrophy (DMD).
Eliška Macků +2 more
doaj +1 more source
Oral motor deficits in speech-impaired children with autism [PDF]
Absence of communicative speech in autism has been presumed to reflect a fundamental deficit in the use of language, but at least in a subpopulation may instead stem from motor and oral motor issues.
Lisa eGeorge +7 more
core +2 more sources
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Life satisfaction and self-efficacy in patients affected by a first stroke living in Kuwait: A two-phase study [PDF]
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2012 Informa Healthcare USA, Inc.Life satisfaction and self-efficacy are important aspects of stroke rehabilitation.
Omu, O, Reynolds, F
core +1 more source
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
Digital Technology Supporting Children's Speech Therapy
Considering that all children are attracted to technology and spend a lot of time using digital technology, it would be advisable to use IT support for education and/or therapy.
Mihaela CRIŞAN-VIDA +3 more
doaj

