Results 71 to 80 of about 320,397 (306)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Who really decides? Feeding decisions ‘made’ by caregivers of children with cerebral palsy

South African Journal of Communication Disorders
Background: There are no definitive guidelines for clinical decisions for children with cerebral palsy (CP) requiring enteral feeds. Traditionally, medical doctors made enteral feeding decisions, while patients were essentially treated passively within a
Lavanya Naidoo, Mershen Pillay, Urisha Naidoo   +2 more
doaj   +1 more source

The Inclusion of Music Therapy in Speech-Language Interventions [PDF]

, 2015
The purpose of this study was to investigate the inclusion of music in speech-language therapy. One hundred practicing speech-language pathologists (SLPs) participated in the study.
Farnell, Torry
core   +1 more source

Accessibility of computer therapy and technology for people with aphasia [PDF]

, 2014
Language difficulties present within aphasia can substantially affect a user’s ability to access and interact with technology. Surprisingly however, there is comparatively little research into the impact of this condition upon accessibility.
Roper, A.
core   +1 more source

Speech and language therapy interventions for children with primary speech and/or language disorders [PDF]

Cochrane Database of Systematic Reviews, 2017
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To determine the effectiveness of speech and language therapy interventions for children with a primary diagnosis of speech and/or language disorders. The review will focus on comparisons between active interventions and controls.
Law, J, Dennis, JA, Charlton, JJV
openaire   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

The effect of mild-stage Alzheimer’s disease on the acoustic parameters of voice

The Egyptian Journal of Otolaryngology
Objective Our study aimed to reveal the differences by comparing the objective and subjective voice features of individuals diagnosed with mild-stage Alzheimer’s disease (AD) with those with normal cognitive abilities.
Emel Arslan-Sarımehmetoğlu, Elife Barmak   +1 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Perceived barriers to compliance with speech-language therapist dysphagia recommendations of South African nurses

South African Journal of Communication Disorders, 2020
Background: Literature has shown that there is limited compliance amongst nurses with the dysphagia recommendations made by speech-language therapists (SLTs).
Andrea Robbertse, Alida de Beer
doaj   +1 more source

Increasing appropriate social communication and pragmatic language skills in young adults with autism spectrum disorders [PDF]

, 2016
This report seeks to explore intervention methodologies that can be adapted for use with young transitional adults with Autism Spectrum Disorders (ASD) to increase appropriate social communication.
Coppock, Amanda Rene'
core   +1 more source