Results 71 to 80 of about 319,390 (306)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Brain SciencesCurrently, in the field of rehabilitation, there is a need for researchers and clinicians to stay updated on recent knowledge worldwide [...]
Dionysios Tafiadis +3 more
doaj +1 more source
Evidence Based Systematic Review of Aphasia Therapy for bilingual individuals [PDF]
, 2010 Relatively little is known about the best practices for language therapy in bilingual aphasia. This systematic review examined three crucial questions faced by speech-language pathologists during clinical decision making: outcomes when language therapy ...
Faroqi-Shah, Yasmeen +3 more
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Spanish-English Bilingual Speech Therapy: A Review of Availability, Practice, and Need [PDF]
, 2017 Spanish-English bilingual speech therapy is a growing field in the United States, especially in the public school system. The Spanish speaking population in America is increasing, and Spanish-English bilingual children require different speech ...
Lormis, Bethany D
core
Oral Intake of hospitalized patient with neurogenic oropharyngeal dysphagia [PDF]
, 2010 PURPOSE: to investigate the development in oral intake and the incidence of bronchopneumonia (BCP) in hospitalized patients with neurogenic oropharyngeal dysphagia, after speech and language therapy intervention.
Gonçalves, Maria Inês Rebelo +2 more
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Effects of hippotherapy on motor function of children with cerebral palsy: a systematic review study
Italian Journal of PediatricsCerebral palsy includes a spectrum of neurodevelopmental disorders caused by brain damage, leading to impairment of movement, posture, and balance for a lifetime. There are many therapeutic interventions for cerebral palsy.
Panagiotis Plotas +14 more
doaj +1 more source