Results 71 to 80 of about 80,071 (286)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Validation of the Brief Autism Mealtime Behavior Inventory in Parents of Children in Cyprus

Children
Background/Objectives: Autism Spectrum Disorder (ASD) includes significant feeding difficulties, behavioral issues, and communication deficits that are linked to serious medical complications and developmental challenges.
Andri Papaleontiou, Vassiliki Siafaka, Louiza Voniati, Alexandros Gryparis, Rafaella Georgiou, Dionysios Tafiadis   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Compulsory community service for speech-language and hearing therapy professionals : readiness, reality and readjustment [PDF]

, 2011
Thesis (MPhill)--University of Stellenbosch, 2011.ENGLISH ABSTRACT: Compulsory Community Service for the speech-language and hearing therapy profession was implemented in 2003.
Wranz, Elsie Sophia
core  

Fuzzy Cognitive Maps for Decision Support in Post-COVID Syndrome with Speech-Language Pathology-Related Problems

Applied Sciences
Detecting and managing speech-language pathology symptoms in patients with post-COVID syndrome (long COVID) presents a significant challenge, as the condition is marked by persistent and varied symptoms such as cognitive deficits, communication ...
Manila Tola, Voula Chris Georgopoulos, Eleftheria Geronikou, Panagiotis Plotas, Chrysostomos Stylios   +4 more
doaj   +1 more source

Perceived barriers to compliance with speech-language therapist dysphagia recommendations of South African nurses

South African Journal of Communication Disorders, 2020
Background: Literature has shown that there is limited compliance amongst nurses with the dysphagia recommendations made by speech-language therapists (SLTs).
Andrea Robbertse, Alida de Beer
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Comparing Traditional Service Delivery and Telepractice for Speech Sound Production Using a Functional Outcome Measure

, 2018
Purpose Using American Speech-Language-Hearing Association's (ASHA's) National Outcomes Measurement System (NOMS) Functional Communication Measure (FCM) as a common metric, this investigation compared traditional service delivery
Parham, Douglas F., Jared Reyes, Douglas Parham, Melissa Jakubowitz, Howell, Cassandra, Jakubowitz, Melissa, Cassandra Howell, Kathy Coufal, Coufal, Kathy L., Reyes, Jared   +9 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source