Results 111 to 120 of about 7,706,916 (368)

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita   +8 more
wiley   +1 more source

Single-channel speech enhancement based on joint constrained dictionary learning

EURASIP Journal on Audio, Speech, and Music Processing, 2021
To improve the performance of speech enhancement in a complex noise environment, a joint constrained dictionary learning method for single-channel speech enhancement is proposed, which solves the “cross projection” problem of signals in the joint ...
Linhui Sun, Yunyi Bu, Pingan Li, Zihao Wu   +3 more
doaj   +1 more source

Cauchy Multichannel Speech Enhancement with a Deep Speech Prior [PDF]

2019 27th European Signal Processing Conference (EUSIPCO), 2019
We propose a semi-supervised multichannel speech enhancement system based on a probabilistic model which assumes that both speech and noise follow the heavy-tailed multi-variate complex Cauchy distribution. As we advocate, this allows handling strong and adverse noisy conditions.
Fontaine, Mathieu, Nugraha, Aditya Arie, Badeau, Roland, Yoshii, Kazuyoshi, Liutkus, Antoine   +4 more
openaire   +3 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

VSEGAN: Visual Speech Enhancement Generative Adversarial Network [PDF]

arXiv, 2021
Speech enhancement is an essential task of improving speech quality in noise scenario. Several state-of-the-art approaches have introduced visual information for speech enhancement,since the visual aspect of speech is essentially unaffected by acoustic environment.
arxiv  

Investigating the Neural Basis of Audiovisual Speech Perception with Intracranial Recordings in Humans [PDF]

, 2017
Speech is inherently multisensory, containing auditory information from the voice and visual information from the mouth movements of the talker. Hearing the voice is usually sufficient to understand speech, however in noisy environments or when audition ...
Sertel, Muge O
core   +1 more source

Speech Enhancement

Speech disfluencies encompass a wide array of interruptions and irregularities that can disrupt the natural flow of spoken language. These disruptions manifest in various forms, including silent pauses, prolongations, repetitions of words, and the insertion of hesitation markers like "um" and "uh." Such interruptions pose significant challenges in ...
Jeyadev Needhi, Ram Prasath G, Mohamed Riffath K, Manokar S   +3 more
openaire   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

Deep neural network techniques for monaural speech enhancement: state of the art analysis [PDF]

arXiv, 2022
Deep neural networks (DNN) techniques have become pervasive in domains such as natural language processing and computer vision. They have achieved great success in these domains in task such as machine translation and image generation. Due to their success, these data driven techniques have been applied in audio domain.
arxiv  

Comparison of Speech Enhancement Algorithms

Procedia Computer Science, 2016
AbstractThe simplest and very familiar method to take out stationary background noise is spectral subtraction. In this algorithm, a spectral noise bias is calculated from segments of speech inactivity and is subtracted from noisy speech spectral amplitude, retaining the phase as it is.
Siddala Vihari, ., Sreenivasa Murthy, A., Priyanka Soni, ., Naik, D.C   +3 more
openaire   +3 more sources