Results 31 to 40 of about 75,405 (258)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Understanding the nature of apraxia of speech: Theory, analysis, and treatment

Neuropsychological Trends, 2010
Researchers have interpreted the behaviours of individuals with acquired apraxia of speech (AOS) as impairment of linguistic phonological processing, motor control, or both.
Kirrie J. Ballard, Jay P. Granier, Donald A. Robin   +2 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

A review of acoustic studies on the nature of speech errors in individuals with Broca’ aphasia

مجله پژوهش در علوم توانبخشی, 2015
Introduction: Broca’s aphasia is one of the types of non-fluent aphasia that its main feature is imprecise speech sound productions. Different surveys have shown that patients with Broca’s aphasia have defects which can affect sound structure in their ...
Fatemeh Abnavi, Leila Ghasisin
doaj   +1 more source

A Simple 3-Parameter Model for Examining Adaptation in Speech and Voice Production

Frontiers in Psychology, 2020
Sensorimotor adaptation experiments are commonly used to examine motor learning behavior and to uncover information about the underlying control mechanisms of many motor behaviors, including speech production.
Elaine Kearney, Alfonso Nieto-Castañón, Hasini R. Weerathunge, Riccardo Falsini, Ayoub Daliri, Defne Abur, Kirrie J. Ballard, Soo-Eun Chang, Soo-Eun Chang, Sara-Ching Chao, Elizabeth S. Heller Murray, Terri L. Scott, Frank H. Guenther, Frank H. Guenther, Frank H. Guenther, Frank H. Guenther   +15 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

GEPPETO-OFC: An optimal feedback speech motor control model integrating biomechanical constraints and multisensory goal specification [PDF]

JASA Express Letters
We present a speech motor control model that integrates optimal feedback control (OFC) for movement planning and execution with a biomechanical model of the vocal tract.
Ny Tsiky Rakotomalala, Pierre Baraduc, Pascal Perrier   +2 more
doaj   +1 more source

Speech Kinematics and Coordination Measured With an MEG-Compatible Speech Tracking System

Frontiers in Neurology, 2022
Articulography and functional neuroimaging are two major tools for studying the neurobiology of speech production. Until recently, however, it has generally not been possible to use both in the same experimental setup because of technical ...
Ioanna Anastasopoulou, Pascal van Lieshout, Douglas O. Cheyne, Douglas O. Cheyne, Blake W. Johnson   +4 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source