Results 101 to 110 of about 118,630 (265)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

ADscreen: A speech processing-based screening system for automatic identification of patients with Alzheimer's disease and related dementia. [PDF]

Artif Intell Med, 2023
Zolnoori M, Zolnour A, Topaz M.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

A dataset of synthetic art dialogues with ChatGPT

Scientific Data
This paper introduces Art_GenEvalGPT, a novel dataset of synthetic dialogues centered on art generated through ChatGPT. Unlike existing datasets focused on conventional art-related tasks, Art_GenEvalGPT delves into nuanced conversations about art ...
Manuel Gil-Martín, Cristina Luna-Jiménez, Sergio Esteban-Romero, Marcos Estecha-Garitagoitia, Fernando Fernández-Martínez, Luis Fernando D’Haro   +5 more
doaj   +1 more source

Degraded and computer-generated speech processing in a bonobo. [PDF]

Anim Cogn, 2022
Lahiff NJ, Slocombe KE, Taglialatela J, Dellwo V, Townsend SW.   +4 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

An autoencoder and vision transformer based interpretability analysis on the performance differences in automated staging of second and third molars

Scientific Reports
The practical adoption of deep learning in high-stakes forensic applications, such as dental age estimation, is often limited by the ‘black box’ nature of the models. This study introduces a framework designed to enhance both performance and transparency
Barkin Buyukcakir, Jannick De Tobel, Patrick Thevissen, Dirk Vandermeulen, Peter Claes   +4 more
doaj   +1 more source

Metamodal Coupling of Vibrotactile and Auditory Speech Processing Systems through Matched Stimulus Representations. [PDF]

J Neurosci, 2023
Damera SR, Malone PS, Stevens BW, Klein R, Eberhardt SP, Auer ET, Bernstein LE, Riesenhuber M.   +7 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

The effect of noise on the cortical activity patterns of speech processing in adults with single-sided deafness. [PDF]

Front Neurol, 2023
Han JH, Lee J, Lee HJ.
europepmc   +1 more source