Results 81 to 90 of about 3,919,398 (308)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Dysarthric speech classification using glottal features computed from non-words, words and sentences

open access: yes, 2018
Dysarthria is a neuro-motor disorder resulting from the disruption of normal activity in speech production leading to slow, slurred and imprecise (low intelligible) speech.
Narendra N P   +3 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Effective Acoustic Model-Based Beamforming Training for Static and Dynamic Hri Applications

open access: yesSensors
Human–robot collaboration will play an important role in the fourth industrial revolution in applications related to hostile environments, mining, industry, forestry, education, natural disaster and defense.
Alejandro Luzanto   +5 more
doaj   +1 more source

Multimedia Quality as Perceived by the User

open access: yesCommunications, 2008
End-to-end voice quality as perceived by the user has always been of major concern to ETSI, the European Telecommunications Standards Institute and its Technical Committee STQ (Speech processing, Transmission and Quality aspects).
Jean-Yves Monfort   +3 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Sound Privacy: A Conversational Speech Corpus for Quantifying the Experience of Privacy

open access: yes, 2019
With the growing popularity of social networks, cloud services and online applications, people are becoming concerned about the way companies store their data and the ways in which the data can be applied.
Das, Sneha   +9 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Adaptive Multi-Objective Optimization-Based Coverage Path Planning Method for UUVs

open access: yes水下无人系统学报
Coverage path planning for unmanned undersea vehicles(UUVs) in unknown aquatic environments is a critical task. However, due to environmental uncertainties, motion constraints, and energy limitations, traditional path planning methods struggle to adapt ...
Shaojing ZHAO   +4 more
doaj   +1 more source

Visual speech influences speeded auditory identification

open access: yes, 2011
Auditory speech perception is faster and more accurate when combined with visual speech. We attempted to replicate previous findings that suggested visual speech facilitates auditory processing when speech is paired with matching video and interferes ...
Paris, Tim (S30187)   +2 more
core  

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