Results 71 to 80 of about 173,179 (314)

End-to-End Optimized Multi-Stage Vector Quantization of Spectral Envelopes for Speech and Audio Coding

, 2021
Spectral envelope modeling is an instrumental part of speech and audio codecs, which can be used to enable efficient entropy coding of spectral components.
Bäckström, Tom, Vali, Mohammadhassan, Mohammad Hassan Vali, Tom Bäckström   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Blind Subband Beamforming With Time-Delay Constraints for Moving Source Speech Enhancement

, 2007
A new robust microphone array method to enhance speech signals generated by a moving person in a noisy environment is presented. This blind approach is based on a two-stage scheme.
Yermeche, Zohra, Claesson, Ingvar, Grbic, Nedelko   +2 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Objective Evaluation of Prosody and Intelligibility in Speech Synthesis via Conditional Prediction of Discrete Tokens

IEEE Open Journal of Signal Processing
Objective evaluation of synthesized speech is critical for advancing speech generation systems, yet existing metrics for intelligibility and prosody remain limited in scope and weakly correlated with human perception.
Ismail Rasim Ulgen, Zongyang Du, Junchen Lu, Philipp Koehn, Berrak Sisman   +4 more
doaj   +1 more source

Complex-Valued Independent Component Analysis for Online Blind Speech Extraction

, 2008
This paper presents a theoretical analysis of a certain criterion for complex-valued independent component analysis (ICA) with a focus on blind speech extraction (BSE) of a spatio–temporally nonstationary speech source.
Sällberg, Benny, Claesson, Ingvar, Grbic, Nedelko   +2 more
core   +1 more source

Glottal features for classification of phonation type from speech and neck surface accelerometer signals

, 2021
Glottal source characteristics vary between phonation types due to the tension of laryngeal muscles with the respiratory effort. Previous studies in the classification of phonation type have mainly used speech signals recorded by microphone.
Kadiri, Sudarsana Reddy, Alku, Paavo
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Phoneme and sentence-level ensembles for speech recognition

, 2011
We address the question of whether and how boosting and bagging can be used for speech recognition. In order to do this, we compare two different boosting schemes, one at the phoneme level and one at the utterance level, with a phoneme-level bagging ...
Dimitrakakis, Christos, Bengio, Samy, Samy Bengio, Dimitrakakis, Christos,, Bengio, S., Christos Dimitrakakis   +5 more
core   +1 more source