Results 71 to 80 of about 22,657 (266)

Effects of tonsillectomy under general anaesthesia on articulatory characteristics and blood levels of PCT, GMP-140, and T lymphocyte subsets in children with obstructive sleep apnea-hypopnea syndrome [PDF]

精准医学杂志
Objective To explore the effects of tonsillectomy under general anesthesia on articulatory characteristics and blood levels of procalcitonin (PCT), platelet membrane protein-140 (GMP-140), and T lymphocyte subsets in children with obstructive sleep apnea-
WANG Zihan, PAN Hongshuai
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Aquisição da coda vibrante: o estabelecimento de pistas fonético-acústicas Vibrant coda acquisition: the establishment of acoustic‑phonetic cues

Revista da Sociedade Brasileira de Fonoaudiologia, 2012
OBJETIVO: Caracterizar acusticamente as produções da coda vibrante julgadas auditivamente como alvo; identificar a existência ou não de contrastes encobertos, nas produções julgadas auditivamente como tendo omissão da coda vibrante; e, quando existentes,
Larissa Cristina Berti, Larriane Karen de Campos   +1 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Comparison of plosive sounds in monolingual and bilingual children, using the voice onset time acoustic parameter: cases report

Revista CEFAC
The purpose was to compare differences in production of plosive phonemes through the voice onset time (VOT) measurement in the speech of monolingual children, speakers of Brazilian Portuguese and bilingual children, speakers of both Brazilian Portuguese ...
Maria Teresa R. Lofredo-Bonatto, Marta A. Andrada e Silva   +1 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Facial Movements Extracted from Video for the Kinematic Classification of Speech

Sensors
Speech Sound Disorders (SSDs) are prevalent communication problems in children that pose significant barriers to academic success and social participation. Accurate diagnosis is key to mitigating life-long impacts.
Richard Palmer, Roslyn Ward, Petra Helmholz, Geoffrey R. Strauss, Paul Davey, Neville Hennessey, Linda Orton, Aravind Namasivayam   +7 more
doaj   +1 more source

Características da fonetografia em coristas de diferentes classificações vocais Phonetography characteristics of choristers with different vocal classifications

Revista da Sociedade Brasileira de Fonoaudiologia, 2007
OBJETIVO: Caracterizar a dinâmica vocal por meio da fonetografia em coristas de diferentes classificações vocais. MÉTODOS: Participaram 44 indivíduos, de 19 a 75 anos (média=51,9 anos) membros de um coral profissional; sendo, oito sopranos, 20 mezzo ...
Thatiana Francisco de Camargo, Daniela Aparecida Barbosa, Lídia Cristina da Silva Teles   +2 more
doaj   +1 more source