Results 71 to 80 of about 263,095 (308)
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Scientific Reports, 2022 A numerical simulation of sibilant /s/ production with the realistically moving vocal tract was conducted to investigate the flow and acoustic characteristics during the articulation process of velopharyngeal closure and tongue movement. The articulation
HsuehJui Lu +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
The current state of biomarker research for Friedreich's ataxia: a report from the 2018 FARA biomarker meeting [PDF]
, 2019 The 2018 FARA Biomarker Meeting highlighted the current state of development of biomarkers for Friedreich's ataxia. A mass spectroscopy assay to sensitively measure mature frataxin (reduction of which is the root cause of disease) is being developed ...
Blair, Ian A. +8 more
core +1 more source
Speech Production Measures in Brazilian Portuguese Children With and Without Speech Sound Disorder
, 2023 Processo FAPESP: 2016/19888 ...
Oliveira, Aline Mara de +5 more
openaire +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Systematic studies of modified vocalization: the effect of speech rate on speech production measures during metronome‐paced speech in persons who stutter [PDF]
International Journal of Language & Communication Disorders, 2013 AbstractBackgroundMetronome‐paced speech results in the elimination, or substantial reduction, of stuttering moments. The cause of fluency during this fluency‐inducing condition is unknown. Several investigations have reported changes in speech pattern characteristics from a control condition to a metronome‐paced speech condition, but failure to ...
openaire +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Revista CEFAC, 2007 OBJETIVO: comparar a extensão vocal de idosos coralistas e não coralistas e analisar a influência da prática do canto-coral amador na extensão vocal dos mesmos.
Tatiana Fernandes Rocha +2 more
doaj +1 more source
Working memory and working attention: What could possibly evolve? [PDF]
, 2010 The concept of “working” memory is traceable back to nineteenth century theorists (Baldwin, 1894; James 1890) but the term itself was not used until the mid-twentieth century (Miller, Galanter & Pribram, 1960).
Beaman, Charles Philip
core +1 more source