Results 61 to 70 of about 263,095 (308)

Patterns of variability in voice onset time: a developmental study of motor speech skills in humans [PDF]

open access: yes, 2003
This study investigated the developmental patterns of variability in the speech parameter voice onset time (VOT) in forty six children. Five groups of children participated in the study as follows: i) Group 1 - aged 5 years 8 months (n=6); ii) Group 2 ...
Auzou   +19 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Voice and speech functions (B310-B340) [PDF]

open access: yes, 2012
The International Classification of Functioning, Disability and Health for Children and Youth (ICF-CY) domain ‘voice and speech functions’ (b3) includes production and quality of voice (b310), articulation functions (b320), fluency and rhythm of speech ...
McCartney, Elspeth
core  

“Product” Versus “Process” Measures in Assessing Speech Recognition Outcomes in Adults With Cochlear Implants [PDF]

open access: yesOtology & Neurotology, 2018
Hypotheses: 1) When controlling for age in postlingual adult cochlear implant (CI) users, information-processing functions, as assessed using “process” measures of working memory capacity, inhibitory control, information-processing speed, and fluid reasoning, will predict traditional “product” outcome measures of speech ...
Aaron C, Moberly   +4 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Local field potentials in a pre-motor region predict learned vocal sequences.

open access: yesPLoS Computational Biology, 2021
Neuronal activity within the premotor region HVC is tightly synchronized to, and crucial for, the articulate production of learned song in birds. Characterizations of this neural activity detail patterns of sequential bursting in small, carefully ...
Daril E Brown   +7 more
doaj   +1 more source

Investigating the native speaker phenomenon – a pilot corpus study of native and non-native writing [PDF]

open access: yes, 2011
The aim of this report is to provide a preliminary account of the investigation of two general corpora of written English, which was prompted originally by interest in an analytical tool designed to assess the propositional density in the utterances of ...
Krakowian, Przemysław
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Singing synthesis with an evolved physical model [PDF]

open access: yes, 2006
A two-dimensional physical model of the human vocal tract is described. Such a system promises increased realism and control in the synthesis. of both speech and singing.
Cooper, Crispin   +3 more
core   +1 more source

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