Results 61 to 70 of about 179,180 (260)

A STUDY ON THE EFFECT OF SLOWER SPEECH RATE PRODUCED BY THE SPEECH RATE CONVERTER

open access: yesNippon Jibiinkoka Gakkai Kaiho, 1996
This study was concerned with the effect of the speech rate converter, invented by cooperation of NHK Science and technical research laboratories with the ENT Department, Tokyo Medical College. The converter can make the speech rate up to 1.6 times slower with little change in voice quality and personal features, so that the spoken language can be ...
openaire   +3 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Talking Like a Teacher—A Study of Pre-Service Teachers’ Voice and Speech Characteristics in Learning and Teaching Situations

open access: yesEducation Sciences
Voice and speech are educational tools and a medium of pedagogy for teachers. Teachers tend to modify their voice and speech to support learning. This study aimed to investigate whether pre-service teachers modify their speech and voice in teaching ...
Kati Järvinen   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Expression of basic emotions in Estonian parametric text-to-speech synthesis

open access: yesEesti ja Soome-ugri Keeleteaduse Ajakiri, 2015
The goal of this study was to conduct modelling experiments, the purpose of which was the expression of three basic emotions (joy, sadness and anger) in Estonian parametric text-to-speech synthesis on the basis of both a male and a female voice. For each
Kairi Tamuri, Meelis Mihkla
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Perceived Difficulties in TOEFL Listening: A Diagnostic Study of Indonesian EFL Learners at UNAI

open access: yesAcuity
Indonesian EFL undergraduates at faith-based Universitas Advent Indonesia (UNAI) face persistent TOEFL listening challenges, yet institution-specific diagnostics remain scarce.
Nelson Balisar Panjaitan
doaj   +1 more source

Can you hear my age? Influences of speech rate and speech spontaneity on estimation of speaker age

open access: yesFrontiers in Psychology, 2015
Cognitive hearing science is mainly about the study of how cognitive factors contribute to speech comprehension, but cognitive factors also partake in speech processing to infer non-linguistic information from speech signals, such as the intentions of ...
Sara eWaller Skoog   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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