Results 71 to 80 of about 179,180 (260)
Foreign Languages Sound Fast: Evidence from Implicit Rate Normalization
Frontiers in Psychology, 2017 Anecdotal evidence suggests that unfamiliar languages sound faster than one’s native language. Empirical evidence for this impression has, so far, come from explicit rate judgments.
Hans Rutger Bosker +2 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Beyond Verbal Behavior: An Empirical Analysis of Speech Rates in Psychotherapy Sessions
Frontiers in Psychology, 2018 Objective: The present work aims to detect the role of the rate of speech as a mechanism able to give information on patient's intrapsychic activity and the intersubjective quality of the patient–therapist relationship.Method: Thirty clinical sessions ...
Diego Rocco +5 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Effects of speech rate and practice on the allocation of visual attention in multiple object naming
Frontiers in Psychology, 2012 Earlier studies had shown that speakers naming several objects typically look at each object until they have retrieved the phonological form of its name and therefore look longer at objects with long names than at objects with shorter names.
Antje eMeyer +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Accommodation in learner corpora: A case study in phonetic convergence
Anglophonia, 2017 Phonetic convergence is the process by which a speaker adapts his speech to sound more similar to his/her interlocutor. While most studies analyzing this process have been conducted amongst speakers sharing the same language or variety, this preliminary ...
Léa Burin, Nicolas Ballier
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
User speech rates and preferences for system speech rates
International Journal of Human-Computer Studies, 2023 Stewart Dowding +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source