Results 41 to 50 of about 227,711 (241)
Abstract Objectives Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cognitive function in a well characterized cohort of patients with a biomarker‐based diagnosis.
Adrià Tort‐Merino+16 more
wiley +1 more source
End-to-End Neural Systems for Automatic Children Speech Recognition: An Empirical Study [PDF]
A key desiderata for inclusive and accessible speech recognition technology is ensuring its robust performance to children's speech. Notably, this includes the rapidly advancing neural network based end-to-end speech recognition systems. Children speech recognition is more challenging due to the larger intra-inter speaker variability in terms of ...
arxiv
Lip reading is used to understand or interpret speech without hearing it, a technique especially mastered by people with hearing difficulties. The ability to lip read enables a person with a hearing impairment to communicate with others and to engage in social activities, which otherwise would be difficult.
openaire +4 more sources
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric+11 more
wiley +1 more source
Improving Children's Speech Recognition by Fine-tuning Self-supervised Adult Speech Representations [PDF]
Children's speech recognition is a vital, yet largely overlooked domain when building inclusive speech technologies. The major challenge impeding progress in this domain is the lack of adequate child speech corpora; however, recent advances in self-supervised learning have created a new opportunity for overcoming this problem of data scarcity.
arxiv
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen+17 more
wiley +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Speech Enhancement Modeling Towards Robust Speech Recognition System [PDF]
Form about four decades human beings have been dreaming of an intelligent machine which can master the natural speech. In its simplest form, this machine should consist of two subsystems, namely automatic speech recognition (ASR) and speech understanding (SU).
arxiv
Evaluating Speech Synthesis by Training Recognizers on Synthetic Speech [PDF]
Modern speech synthesis systems have improved significantly, with synthetic speech being indistinguishable from real speech. However, efficient and holistic evaluation of synthetic speech still remains a significant challenge. Human evaluation using Mean Opinion Score (MOS) is ideal, but inefficient due to high costs.
arxiv
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda+3 more
wiley +1 more source