Results 91 to 100 of about 6,690,892 (354)
Investigation of the Specht density estimator [PDF]
The feasibility of using the Specht density estimator function on the IBM 360/44 computer is investigated. Factors such as storage, speed, amount of calculations, size of the smoothing parameter and sample size have an effect on the results.
Rydl, L. M., Speed, F. M.
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
International Journal of Chemical Engineering, 2018 The air-flow impacting based mechanochemical synthesis is an alternative strategy to traditional mechanochemical preparations, which has many advantages in terms of reaction temperature, preparation speed, and cleanness.
Yang Tao +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 1968 Miniaturized, 16 mm high speed pulse camera takes spectral photometric photographs upon instantaneous command. The design includes a low-friction, low-inertia film transport, a very thin beryllium shutter driven by a low-inertia stepper motor for ...
Lawson, J. R.
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Anchored expansion, percolation and speed
, 2004 Benjamini, Lyons and Schramm [Random Walks and Discrete Potential Theory (1999) 56-84] considered properties of an infinite graph G, and the simple random walk on it, that are preserved by random perturbations.
Chen, Dayue, Peres, Yuval, Pete, Gabor
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Discourse Analysis: varieties and methods [PDF]
, 2009 This paper presents and analyses six key approaches to discourse analysis, including political discourse theory, rhetorical political analysis, the discourse historical approach in critical discourse analysis, interpretive policy analysis, discursive ...
Glynos, J +3 more
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