Results 121 to 130 of about 6,690,892 (354)

Calculation and uncertainty analysis method for airfoil drag coefficient considering compressibility

open access: yesAIP Advances
In order to meet the need of evaluating the effectiveness of airfoil drag reduction design, the calculation and uncertainty analysis method for airfoil drag coefficient considering compressibility is studied.
Yufeng Du   +4 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Measured speed versus true speed

open access: yes, 2010
The theoretical predictions, derived from the Lorentz and the Tangherlini transformations, for the one-way speed of any physical entity are confronted with the corresponding expressions for the one-way measured speed obtained from a gedanken experiment. The experiment demonstrates that, for an inertial frame $K'$ in motion relative to an inertial frame
openaire   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

LOW LEVEL LASER THERAPY: HEALING AT THE SPEED OF LIGHT

open access: bronze, 2013
Samith Ahmed   +3 more
openalex   +1 more source

Reynolds Number Effect of a Supercritical Wing Based on Cryogenic and High Reynolds Number Pressure Test

open access: yesAerospace
Supercritical wings are widely used in large aircraft due to their excellent transonic performance, but their aerodynamic characteristics are highly sensitive to Reynolds number. To systematically study the influence of Reynolds number on the aerodynamic
Baobin Hou   +5 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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