Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Association Between Cervical Range of Motion and Swallowing Speed in Older Women After Total Hip Arthroplasty: A Cross-Sectional Study. [PDF]
Physiother Res IntNakamura K +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Measurement Agreement and Reliability of the 6-m Gait Speed Test in Adult Population: The ADULT-FIT Project. [PDF]
Eur J Sport SciCastro-Piñero J +6 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Design and performance evaluation of a solar powered remote controlled robot for precision seed planting. [PDF]
Sci RepAboharg S +5 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The Kingdome of Scotland [cartographic material] /
, 1900 Facsimile reproduction of John Speed's 1610 map of Scotland, on faux parchment paper, showing county boundaries, settlements and topography. Relief shown pictorially.; Inset: The Yles of Orknay [i.e. Orkney Islands]. Scale [ca.
Speed, John, 1552?-1629.
core
Alterations in Spatiotemporal Parameters in Patients With Lower-Limb Amputation: A Systematic Review With Meta-Analysis. [PDF]
Physiother Res IntFontes LAM +4 more
europepmc +1 more source