Results 51 to 60 of about 1,766,809 (314)

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

112-Gb/s DSP-Based PAM-4 Transceivers for Large-Scale Ethernet Switching Systems

IEEE Open Journal of the Solid-State Circuits Society
As modern ASICs integrate several hundred interconnect ports in a large package, ASIC Serdes design faces challenging performance, power, and area targets.
Henry Park, Mohammed Abdullatif, Ehung Chen, Tamer Ali   +3 more
doaj   +1 more source

Quantum speed limit with forbidden speed intervals [PDF]

Physical Review A, 2013
Quantum mechanics imposes fundamental constraints known as quantum speed limits (QSLs) on the information processing speed of all quantum systems. Every QSL known to date comes from the restriction imposed on the evolution time between two quantum states through the value of a single system observable such as the mean energy relative to its ground ...
openaire   +4 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Entre la antropología y los derechos humanos. Hacia una investigación activista y comprometida críticamente

Alteridades, 2006
This article re examines anthropology’s engagement with humanrights today. Through the lens of the author’s experien-ce in a case brought before the International Labor Or-ganization by a community in Chiapas, Mexico, thiswork considers the ethical ...
SHANNON SPEED
doaj  

Feasibility study and verification of velocity field calibration for short center line probe in subsonic and transonic wind tunnel

Xibei Gongye Daxue Xuebao
According to GJB1179A-2012 "Quality Requirements for Low Speed and High Speed Wind Tunnel Flow Fields", the velocity field calibration is a key item in the wind tunnel flow field calibration and an important basis for evaluating whether wind tunnels have
DENG Haijun, XIONG Bo, LUO Xinfu, LIU Changqing, ZHENG Jieyun   +4 more
doaj   +1 more source