Results 61 to 70 of about 3,031,498 (306)
The speed of light and the speed of neutrinos
Abstract The approximate equality in the arrival times of the neutrino and light signals from SN 1987A allows an accurate check of the hypothesis of special relativity that the limiting velocity for all forms of radiation is the same.
openaire +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Full-Field Displacement Measurements of Helicopter Rotor Blades Using Stereophotogrammetry
This study presents a stereophotogrammetry approach to achieve full-field displacement measurements of helicopter rotor blades. The method is demonstrated in the wind tunnel test of a 2 m diameter rotor, conducted at the 5.5 m×4 m Aeroacoustic Wind ...
Chenglin Zuo +5 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
System-wide inertial response from fixed speed and variable speed wind turbines [PDF]
IEEE PES 2011 General Meeting, Detroit, Michigan, USA, July 24-28, 2011As wind penetration levels on power systems increase worldwide, the dynamic characteristics of these systems are changing due to the displacement of synchronous generation. One issue,
Lisa Ruttledge +3 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Application of pressure scanning valve system in wind tunnel test
In order to study the application characteristics of three typical pressure scanning valve system in wind tunnel environments and provide technical support for related experiments, a systematic research and comparative analysis method was adopted.Wind ...
He Zhenyang +4 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

