Results 221 to 230 of about 51,549 (260)

Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model

open access: yesAdvanced Science, EarlyView.
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen   +15 more
wiley   +1 more source

Disorder‐Induced Extremely Low Thermal Conductivity of Graphite Fluoride

open access: yesAdvanced Science, EarlyView.
This article investigates the effect of fluorination on the thermal conductivity of graphite fluoride, demonstrating the relationship between structural modification and thermal conductivity in an extreme case. The record‐low through‐plane thermal conductivity measured in exfoliated graphite fluoride flakes was found to correlate with the wide ...
Wonsik Lee   +10 more
wiley   +1 more source

Patient Perspectives on Approval Speed vs Evidentiary Certainty in US Cancer Drug Approvals.

open access: yesJAMA Netw Open
Forrest R   +7 more
europepmc   +1 more source

Ethanol, errors, and the speed–accuracy trade-off

Pharmacology Biochemistry and Behavior, 2001
Ethanol has been shown to have a relatively greater effect on error rates in speeded tasks than temazepam, and this may be due to a differential effect on the speed-accuracy trade-off (SATO). This study used different instruction sets to influence the SATO.
Brian Tiplady
exaly   +3 more sources

The speed—accuracy trade-off in industry

Ergonomics, 1994
Abstract In the class of resource-limited tasks, performance speed and accuracy are expected to be inversely related. However at the systems level, interventions which improve quality can provide benefits in throughput. Examining the speed-accuracy operating characteristic (SAOC) of industrial tasks shows that the apparent conflict between these two ...
Colin G Drury
exaly   +2 more sources

Speed–accuracy trade-offs in myocontrol

Human Movement Science, 2006
Myoelectric (EMG) signals are used in assistive technology for prostheses, computer and domestic control. However, little is known about the capacity of controlling these signals. Specifically, it is unclear whether myocontrol, i.e., the control of myoelectric signals, obeys the same laws as motor control.
Eric J, Fimbel   +2 more
openaire   +2 more sources

Adult age and the speed-accuracy trade-off

Ergonomics, 1979
Three experiments were conducted to investigate the possibility that previously reported age differences in speed of performance were caused by older subjects placing more emphasis on accuracy than younger subjects. The speculation that older subjects generally have a greater emphasis on accuracy was confirmed, but only in one of the experiments was ...
openaire   +2 more sources

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