Results 51 to 60 of about 6,364 (304)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Efficiency of noise reduction by a road speed bump
Archives of Acoustics, 2014 The vehicle noise from a road with a bump consists of the deceleration noise, bump noise, and acceleration noise. The bump is modeled by the Dirac delta function.
Rufin MAKAREWICZ, Piotr KOKOWSKI
doaj
Identifikasi Konsep IPA Pada Pemanfaatan Polisi Tidur (Speed Bump) Sebagai Bahan Pembelajaran IPA [PDF]
, 2023 : The purpose of this study is to theoretically review the science concepts that exist in the process of reducing vehicle speed by speedbump and analyze the correlation of material with science learning.
Herman, Dewannia Fariska +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Effectiveness of Motorcycle speed controlled by speed hump
KKU Engineering Journal, 2014 Speed humps are one of the traffic calming measures widely accepted to control vehicle speed in the local road. Humps standards from the western countries are designed mainly for the passenger car.
Pornsiri Urapa +3 more
doaj
Pembangkit Listrik Tenaga Speed Bump Segabai Sumber Energi Alternatif [PDF]
, 2013 Listrik merupakan energi yang mempunyai peran penting dalam kehidupan manusia. PT. PLN sebagai penyedia energi listrik sekarang ini mengalami kesulitan untuk mencukupi kebutuhan energi listrik nasional, hal ini disebabkan karena kebutuhan listrik jauh ...
Munadi, Agus +2 more
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source