Results 151 to 160 of about 6,283,447 (256)

Physics-informed neural network framework for predicting drilling-induced delamination in GFRP composites. [PDF]

PLoS One
Arunadevi M, M S S, B R N M, M C G.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Multi-Objective Optimization of Mechanical Properties for FDM-Printed PLA/TPU Blends via Box-Behnken Design and Entropy Weight Method. [PDF]

Polymers (Basel)
Li P, Wei T, Yang L, Zhao J, Wang S, Wang S.   +5 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Sensitivity analysis of annual energy production and associated economic losses due to external wake effects on offshore wind clusters: A case study of the Shinan offshore wind cluster in southwest sea of Korea. [PDF]

PLoS One
Ryu G, Lee D, Kim J, Han S, Lee JY, Kim YG, Moon CJ.   +6 more
europepmc   +1 more source

The kingdome of China [cartographic material] /

Map of China including Japan as well as the Ile Corea [i.e. the "island" of Korea]. Eastern India is displayed on the left of the map. The map displays many decorative features mainly vignettes at the top showing land-yachts for travelling by land ...
Speed, John, 1552?-1629
core  

Visual scale factor for speed perception

, 2011
International audienceSpeed perception is an important task depending mainly on optic flow that the driver must perform continuously to control his/her vehicle. Unfortunately it appears that in some driving simulators speed perception is under estimated,
Kemeny, Andras, Merienne, Frédéric, Colombet, Florent, Paillot, Damien   +3 more
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Simulation-Based Multi-Factor Noise-Aware Adaptive Pure Pursuit with Causal EKF-SG Pose Preprocessing for Tracked Agricultural Robots. [PDF]

Sensors (Basel)
Liu F, Wu L, Wu Z, Cai G, Wang M, He S.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source