Results 61 to 70 of about 166,142,660 (307)

Impact of COVID-19 on Corporate Cash Holdings and Speed of Adjustment [PDF]

open access: yesJournal of Asset Management and Financing
Cash management is critical for firm value as both cash surpluses and deficits can diminish value. Consequently, firms aim to maintain optimal cash levels by adjusting their actual cash ratios towards target ratios.
Abbas Aflatooni   +2 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Determinants of Corporate Cash Holdings: Evidence from India

open access: yesRamanujan International Journal of Business and Research, 2019
We examine the evolution and determinants of corporate cash holdings of Indian non-financial firms for the period 2001-2016. In contrast to a prominent increase in corporate liquidity levels globally after the global financial crisis, we document a ...
Mr. C.P Gupta, Mr. Prateek Bedi
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Target capital structure and speed of adjustment: a dynamic evidence from Shariah approved firms in Malaysia

open access: yes, 2017
The purpose of this paper is to identify the target capital structure and the speed of adjustment of Shariah approved firms listed on the Bursa Malaysia.
Razali Haron   +3 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

MACROECONOMIC CONDITION AND CAPITAL STRUCTURE ADJUSTMENT SPEED - EVIDENCE FROM INDONESIAN STOCK EXCHANGE

open access: yes, 2012
[[abstract]]This thesis provides analysis of the adjusting behavior for the firms listed in Indonesian stock exchange from 1992 to 2010 when the adjustment speed of capital structure affected bu macroeconomic condition.
RAHIM, RELIA NOVITA
core  

Speed Choice, Speed Preference and Risk Perception: Relevance for the Problem of Speed Variability in Traffic [PDF]

open access: yes, 2014
Fifty percent of drives have been found to frequently violate speed limits (OECD/ECMT, 2006), and speed limit compliance appears to depend on the perceived credibility of a road’s speed limit (Goldenbeld & van Schagen, 2007). Credibility of speed limits,
Ahie, Liv Marit
core  

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