Results 131 to 140 of about 2,323,356 (342)

Multiline Orthogonal Scanning Temporal Focusing (mosTF) Microscopy for Scattering Reduction in High-speed in vivo Brain Imaging [PDF]

, 2023
Yi Xue, Josiah R. Boivin, Dushan N. Wadduwage, Jong Kang Park, Elly Nedivi, Peter T. C. So   +5 more
openalex   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Measurement of Ultra-High Speed by Optical Multistage Cascade Frequency Reduction Technology

Applied Sciences
In order to reduce the frequency of high-frequency Doppler signal light, the electronic bandwidth of a data acquisition system is reduced. This paper mainly describes the principle and experimental verification results of optical multistage cascade ...
Heli Ma, Long Chen, Wei Gu, Cangli Liu, Longhuang Tang, Xing Jia, Tianjiong Tao, Shenggang Liu, Yongchao Chen, Xiang Wang, Jian Wu, Chengjun Li, Dameng Liu, Jidong Weng, Huan Liu   +14 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Inscribed-type spherical speed reducer with uniform reduction ratio in all directions

Results in Engineering
A spherical motor is an actuator that can generate rotational motion about all three orthogonal axes. However, it is difficult to obtain high output torque from most electromagnetic spherical motors, primarily due to limitations inherent in ...
Seiya Naramura, Koichi Tonegawa, So Shimooka, Tomoaki Yano, Akio Gofuku, Nagayoshi Kasashima, Tetsushi Kamegawa   +6 more
doaj   +1 more source

Approximate Reduction of Finite Automata for High-Speed Network Intrusion Detection (Technical Report) [PDF]

, 2017
Milan Češka, Vojtěch Havlena, Lukáš Holík, Ondřej Lengál, Tomáš Vojnar   +4 more
openalex   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

A case study of energy expenditure based on walking speed reduction during walking upstairs situation at a staircase in FKAAS, UTHM, Johor building [PDF]

, 2018
Muhammad Salleh Abustan, Mohd Firdaus Mohamad Ali, Siti Hidayah Abu Talib   +2 more
openalex   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source