Results 111 to 120 of about 2,323,356 (342)

Complexity reduction of astrochemical networks

open access: yes, 2012
We present a new computational scheme aimed at reducing the complexity of the chemical networks in astrophysical models, one which is shown to markedly improve their computational efficiency.
E. Merlin   +19 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

High Speed Balancing Applied to the T700 Engine [PDF]

open access: yes
The work performed under Contracts NAS3-23929 and NAS3-24633 is presented. MTI evaluated the feasibility of high-speed balancing for both the T700 power turbine rotor and the compressor rotor.
Lee, C., Martin, M., Walton, J.
core   +1 more source

Symmetry-Based Search Space Reduction For Grid Maps [PDF]

open access: yes, 2011
In this paper we explore a symmetry-based search space reduction technique which can speed up optimal pathfinding on undirected uniform-cost grid maps by up to 38 times.
Botea, Adi   +2 more
core  

Differential equations on unitarity cut surfaces

open access: yes, 2017
We reformulate differential equations (DEs) for Feynman integrals to avoid doubled propagators in intermediate steps. External momentum derivatives are dressed with loop momentum derivatives to form tangent vectors to unitarity cut surfaces, in a way ...
Zeng, Mao
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evaluation of Traffic Measurements for Speed Reduction

open access: yesINFRASTRUCTURE PLANNING REVIEW, 2005
This paper evaluates the effect of road humps to reduce through traffic and motor-vehicle speeds in residential streets. An experimental scheme to install 22 humps was carried out in Nitshin area in Saga city. These road humps were not useful to reduce through traffic but achieved slower speeds.
Masaru KIYOTA   +3 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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