Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Comfort evaluation and vibration reduction nursing of patients in interhospital transport. [PDF]
Yao M +5 more
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Experimental Investigation of a Tubular Front Cavity for Wind Noise Suppression in MEMS Microphones of Mobile Devices. [PDF]
Sun C, Wei S, Liu B.
europepmc +1 more source
Research on the EEMD-SE-IWTD Combined Noise Reduction Method for High-Speed Transient Complex Features in Acceleration Signals [PDF]
Huifa Shi +5 more
openalex +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Chladni figures reduce ohmic losses in alkaline electrolysis. [PDF]
Agrež V +4 more
europepmc +1 more source
Analysis of the Cogging Torque Reduction in Permanent Magnet Generators for a Very Low Wind Speed
Syamsir Abduh +2 more
openalex +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source

