Results 281 to 290 of about 2,323,356 (342)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A new anti-soiling approach based on oleic acid-modified Al₂O₃ nanocoatings for photovoltaic panels. [PDF]

Sci Rep
Arslan M, Deveci İ, Arslan C, Çunkaş M.   +3 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

NSGA-II-Based Multi-Objective Optimization of Fused Filament Fabrication Process Parameters for TPU Parts with Chemical Smoothing. [PDF]

Polymers (Basel)
Srinivasan L, Radhakrishnan L, Veeranan E, Mohammad FK, Moinuddin SQ, Altammar H.   +5 more
europepmc   +1 more source

Speed of Carbon Deposition in Ore Reduction

Tetsu-to-Hagane, 1964
openaire   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Machine Learning-Assisted Burst Femtosecond Laser Polishing of Invar Alloy: Process Optimization and Performance Enhancement. [PDF]

Nanomaterials (Basel)
Lin J, Li D, Luo J, Li K, Jia X, Wang C, Li X, Sun K, Duan J.   +8 more
europepmc   +1 more source

FUSELAGE SHAPE OPTIMIZATION AIMED AT WING-FUSELAGE CONFIGURATION DRAG REDUCTION AT SUPERSONIC SPEEDS

, 2017
Nikita Ageev, А. А. Павленко
openalex   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Effect of Weight Change on Type 2 Diabetes Risk: A Prospective Study in a Japanese Population.

J Clin Endocrinol Metab
Kagisaki T, Baden MY, Oyama A, Noguchi M, Iso H, Shimomura I.   +5 more
europepmc   +1 more source