Results 81 to 90 of about 645,874 (305)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Zero-speed roll reduction system.

open access: yes, 2018
Zero-speed roll reduction system.
Lihua Liang (82313)   +5 more
core   +1 more source

Estimating the health benefits associated with a speed limit reduction to thirty kilometres per hour: A health impact assessment of noise and road traffic crashes for the Swiss city of Lausanne

open access: yesEnvironment International, 2020
Reductions of speed limits for road traffic are effective in reducing casualties, and are also increasingly promoted as an effective way to reduce noise exposure.The aim of this study was to estimate the health benefits of the implementation of 30 km/h ...
Isabelle A. Rossi   +4 more
doaj   +1 more source

Speed reduction study

open access: yesJournal of Science & Engineering
Civil engineering is a field that focuses on designing, constructing, and maintaining the infrastructure and natural environment that society relies on. Civil engineers have to ensure the safety of all structures and address the concerns of any citizens.
openaire   +1 more source

Automatic Speed Reduction to Avoid Accidents

open access: yesInternational Journal for Research in Applied Science and Engineering Technology, 2021
Abstract: We analyse the automatic braking system to reduce the speed automatically to avoid the panic action of automobiles. Stop the vehicle when it is in the accidental zone, we applied the velocity calculation according to the weight of the body which can reach to required velocity state to avoid the accident.
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Relationship between Speed and Lateral Position on Curves, September 2012

open access: yes, 2012
Excessive speed is often cited as a primary driver factor in crashes, particularly rural two-lane crashes. It has also been suggested that speed plays a significant role in crashes on curves. However, the relationship between speed and crashes on curves

core  

Reflection Reduction on DDR3 High-Speed Bus by Improved PSO

open access: yesThe Scientific World Journal, 2014
The signal integrity of the circuit, as one of the important design issues in high-speed digital system, is usually seriously affected by the signal reflection due to impedance mismatch in the DDR3 bus.
Huiyong Li   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Condition monitoring of slow-speed rolling element bearings using stress waves [PDF]

open access: yes, 2001
Condition monitoring of rolling element bearings through the use of vibration analysis is an established technique for detecting early stages of component degradation. However, this success is not mirrored at rotational speeds below 16r/min.
Mba, David   +2 more
core  

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